Publications
2024
63. Sivarama Prasad Darsi, Somorita Baishya, Veerababu Nagati, Kala Kumar Bharani, Satyanarayana Swamy Cheekatla, Sujesh Kumar Darsi, Adi Reddy Kamireddy, Ram Reddy Barra, Ashok Kumar Devarasetti, Sreedhar Surampudi, Jayaram Reddy Singireddy, Siva Kumar Kandula and Anil Kumar Pasupulati. Safety assessment of rat embryonic fraction for in vivo regenerative therapy. doi:10.1242/bio.060266.
62. Somorita Baishya, Rajat Nath, Deepa Nath, Sumit Saha, Anil K. Pasupulati, Lutfun Nahar, Satyajit D. Sarker, Anupam Das Talukdar. Optimization of extraction using mathematical models and computation.Computational Phytochemistry. https://doi.org/10.1016/B978-0-443-16102-5.00014-6.
61. Sneha Jakhotia, Rajesh Kavvuri, Sumathi Raviraj, Somorita Baishya, Anil Kumar Pasupulati and G. Bhanuprakash Reddy. Obesity-related glomerulopathy is associated with elevated WT1 expression in podocytes. International Journal of Obesity, Springer Nature.
60. Anup S. Pathania, Haritha Chava, Ramesh Balusu, Anil K. Pasupulati,Don W. Coulter, and Kishore B. Challagundla. The crosstalk between non-coding RNAs and cell-cycle events: A new frontier in cancer therapy. Molecular Therapy: Oncology. https://doi.org/10.1016/j.omton.2024.200785.
59. Abrar H Qadri, Jyotsana Prajapati, Iqball Faheem, Utsa Bhattacharjee, Hari Krishnan Padmanaban, Sandeep KN Mulukaka, Anil K Pasupulati. Biophysical characterization and insights into the oligomeric nature of CD2-associated protein.
Int. J Biochem Mol Biol 2024;15(2). doi: 10.62347/UVSH8436
58. Anil K. Pasupulati, Veerababu Nagati, Atreya S.V. Paturi, G. Bhanuprakash Reddy. Non-enzymatic glycation and diabetic kidney disease, Vitamin and Hormones, Academic Press, https://authors.elsevier.com/a/1iYo7J1cUwOyP.
2023
57. Anil K Pasupulati. S Kilari, M Sahay. Editorial: Endocrine Abnormalities and Renal Complications. Front. Endocrinol., 21 August 2023 Sec. Renal Endocrinology Vol 14-2023 https://doi.org/10.3389/fendo.2023.1274669
56. S Katta, VP Nakka, R Kavvuri, AK Pasupulati. Apocynin ameliorates stroke-induced stress in the kidney, Eur. Chem. Bull. 2023,12(4), 3647-3656. doi: 10.48047/ecb/2023.12.4.252
55. Katta, S. S., Nagati, V., Paturi, A. S. V., Murakonda, S. P., Murakonda, A. B., Pandey, M. K., Gupta, S. C., Pasupulati, A.K., & Challagundla, K. B. (2023). Neuroblastoma: Emerging trends in pathogenesis, diagnosis, and therapeutic targets. Journal of Controlled Release, 357, 444–459. https://doi.org/10.1016/j.jconrel.2023.04.001.
2022
54. Nishad, R. et al. (2022) “Podocyte derived tnf‐α mediates monocyte differentiation and contributes to glomerular injury,” The FASEB Journal, 36(12). Available at: https://doi.org/10.1096/fj.202200923r.
53. Kolligundla, L.P. et al. (2022) “Metformin prevents hypoxia‐induced podocyte injury by regulating the zeb2/tg2 axis,” Nephrology [Preprint]. Available at: https://doi.org/10.1111/nep.14121.
52. Mukhi, D. et al. (2022) “Growth hormone induces transforming growth factor-β1 in podocytes: Implications in podocytopathy and proteinuria,” Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, p. 119391. Available at: https://doi.org/10.1016/j.bbamcr.2022.119391.
51. Kolligundla, L., Gupta, S., Lata, S., Mulukala, S., Killaka, P., Akif, M., & Pasupulati, A. (2022). Identification of Novel GTP Analogs as Potent and Specific Reversible Inhibitors for Transglutaminase 2. Molecular Simulation, 1-11. doi: 10.1080/08927022.2022.2123917
50. Pasupulati, A., & Atreya S.V Paturi. (2022). The sponging effect of a lncRNA on a miRNA contributes to diabetic nephropathy. Molecular Therapy - Nucleic Acids, 28, 259-260. doi: 10.1016/j.omtn.2022.03.013
49. Mooli RGR, Mukhi D, Pasupulati AK, Evers SS, Sipula IJ, Jurczak M, Seeley RJ, Shah YM, Ramakrishnan SK. Intestinal HIF-2α Regulates GLP-1 Secretion via Lipid Sensing in L-Cells. Cell Mol Gastroenterol Hepatol. 2022;13(4):1057-1072. doi: 10.1016/j.jcmgh.2021.12.004. Epub 2021 Dec 11. PubMed PMID: 34902628; PubMed Central PMCID: PMC8873605.
2021
48. Mulukala SKN, Kambhampati V, Qadri AH, Pasupulati AK. Evolutionary conservation of intrinsically unstructured regions in slit-diaphragm proteins. PLoS One. 2021;16(7):e0254917. doi: 10.1371/journal.pone.0254917. eCollection 2021. PubMed PMID: 34288970; PubMed Central PMCID: PMC8294545.
47. Nishad R, Tahaseen V, Kavvuri R, Motrapu M, Singh AK, Peddi K, Pasupulati AK. Advanced-Glycation End-Products Induce Podocyte Injury and Contribute to Proteinuria. Front Med (Lausanne). 2021;8:685447. doi: 10.3389/fmed.2021.685447. eCollection 2021. PubMed PMID: 34277660; PubMed Central PMCID: PMC8280521.
46. Singh AK, Kolligundla LP, Francis J, Pasupulati AK. Detrimental effects of hypoxia on glomerular podocytes. J Physiol Biochem. 2021 May;77(2):193-203. doi: 10.1007/s13105-021-00788-y. Epub 2021 Apr 9. Review. PubMed PMID: 33835424.
45. Nishad R, Mukhi D, Singh AK, Motrapu M, Chintala K, Tammineni P, Pasupulati AK. Growth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuria. Cell Death Dis. 2021 Apr 1;12(4):342. doi: 10.1038/s41419-021-03643-6. PubMed PMID: 33795655; PubMed Central PMCID: PMC8016968.
2020
44. Mulukala SKN, Irukuvajjula SS, Kumar K, Garai K, Venkatesu P, Vadrevu R, Pasupulati AK. Structural features and oligomeric nature of human podocin domain. Biochem Biophys Rep. 2020 Sep;23:100774. doi: 10.1016/j.bbrep.2020.100774. eCollection 2020 Sep. PubMed PMID: 32617419; PubMed Central PMCID: PMC7322680.
43. Nishad R, Meshram P, Singh AK, Reddy GB, Pasupulati AK. Activation of Notch1 signaling in podocytes by glucose-derived AGEs contributes to proteinuria. BMJ Open Diabetes Res Care. 2020 Jun;8(1). doi: 10.1136/bmjdrc-2020-001203. PubMed PMID: 32601154; PubMed Central PMCID: PMC7326296.
2019
42. Nakuluri K, Nishad R, Mukhi D, Kumar S, Nakka VP, Kolligundla LP, Narne P, Natuva SSK, Phanithi PB, Pasupulati AK. Cerebral ischemia induces TRPC6 via HIF1α/ZEB2 axis in the glomerular podocytes and contributes to proteinuria. Sci Rep. 2019 Nov 29;9(1):17897. doi: 10.1038/s41598-019-52872-5. PubMed PMID: 31784544; PubMed Central PMCID: PMC6884642.
41. Nishad R, Mukhi D, Tahaseen SV, Mungamuri SK, Pasupulati AK. Growth hormone induces Notch1 signaling in podocytes and contributes to proteinuria in diabetic nephropathy. J Biol Chem. 2019 Nov 1;294(44):16109-16122. doi: 10.1074/jbc.RA119.008966. Epub 2019 Sep 11. PubMed PMID: 31511328; PubMed Central PMCID: PMC6827306.
40. Dolle A, Nagati VB, Hunashal Y, Krishnamurthy K, Pasupulati AK, Raghothama S, Gowd KH. Disulfide engineering on temporin-SHf: Stabilizing the bioactive conformation of an ultra-short antimicrobial peptide. Chem Biol Drug Des. 2019 Sep;94(3):1634-1646. doi: 10.1111/cbdd.13525. Epub 2019 Aug 4. PubMed PMID: 30924306.
39. Nakuluri K, Mukhi D, Nishad R, Saleem MA, Mungamuri SK, Menon RK, Pasupulati AK. Hypoxia induces ZEB2 in podocytes: Implications in the pathogenesis of proteinuria. J Cell Physiol. 2019 May;234(5):6503-6518. doi: 10.1002/jcp.27387. Epub 2018 Sep 21. PubMed PMID: 30238984.
38. Pasupulati AK, Menon RK. Growth hormone and chronic kidney disease. Curr Opin Nephrol Hypertens. 2019 Jan;28(1):10-15. doi: 10.1097/MNH.0000000000000468. Review. PubMed PMID: 30394899.
2018
37. Nakuluri K, Mukhi D, Mungamuri SK, Pasupulati AK. Stabilization of hypoxia-inducible factor 1α by cobalt chloride impairs podocyte morphology and slit-diaphragm function. J Cell Biochem. 2018 Nov 1;. doi: 10.1002/jcb.28041. [Epub ahead of print] PubMed PMID: 30387200.
36. Zhang S, Lu C, Das AK, Pasupulati AK, Menon RK. Abrogation of GH action in Kupffer cells results in increased hepatic CD36 expression and exaggerated nonalcoholic fatty liver disease. Growth Horm IGF Res. 2018 Oct - Dec;42-43:74-79. doi: 10.1016/j.ghir.2018.10.001. Epub 2018 Oct 4. PubMed PMID: 30321786; PubMed Central PMCID: PMC6286732.
35. Sornapudi TR, Nayak R, Guthikonda PK, Pasupulati AK, Kethavath S, Uppada V, Mondal S, Yellaboina S, Kurukuti S. Comprehensive profiling of transcriptional networks specific for lactogenic differentiation of HC11 mammary epithelial stem-like cells. Sci Rep. 2018 Aug 6;8(1):11777. doi: 10.1038/s41598-018-30122-4. PubMed PMID: 30082875; PubMed Central PMCID: PMC6079013.
2017
34. Kamatham S, Pallu R, Pasupulati AK, Singh SS, Gudipalli P. Benzoylsalicylic acid derivatives as defense activators in tobacco and Arabidopsis. Phytochemistry. 2017 Nov;143:160-169. doi: 10.1016/j.phytochem.2017.07.014. Epub 2017 Aug 17. PubMed PMID: 28818753.
33. Mukhi D, Nishad R, Menon RK, Pasupulati AK. Novel Actions of Growth Hormone in Podocytes: Implications for Diabetic Nephropathy. Front Med (Lausanne). 2017;4:102. doi: 10.3389/fmed.2017.00102. eCollection 2017. Review. PubMed PMID: 28748185; PubMed Central PMCID: PMC5506074.
31. Nishad R, Nakuluri K, Motrapu M, Pasupulati A. Epithelial–mesenchymal Transition of Glomerular Podocytes: Implications in Proteinuria. MGM J Med Sci. 2017; 4(1):26-34. doi: 10.5005/jp-journals-10036-113.
2016
30. Kumar Pasupulati A, Chitra PS, Reddy GB. Advanced glycation end products mediated cellular and molecular events in the pathology of diabetic nephropathy. Biomol Concepts. 2016 Dec 1;7(5-6):293-309. doi: 10.1515/bmc-2016-0021. Review. PubMed PMID: 27816946.
29. Mulukala SK, Nishad R, Kolligundla LP, Saleem MA, Prabhu NP, Pasupulati AK. In silico Structural characterization of podocin and assessment of nephrotic syndrome-associated podocin mutants. IUBMB Life. 2016 Jul;68(7):578-88. doi: 10.1002/iub.1515. Epub 2016 May 18. PubMed PMID: 27193387.
28. Kamatham S, Neela KB, Pasupulati AK, Pallu R, Singh SS, Gudipalli P. Benzoylsalicylic acid isolated from seed coats of Givotia rottleriformis induces systemic acquired resistance in tobacco and Arabidopsis. Phytochemistry. 2016 Jun;126:11-22. doi: 10.1016/j.phytochem.2016.03.002. Epub 2016 Mar 14. PubMed PMID: 26988727.
27. Raghu G, Jakhotia S, Yadagiri Reddy P, Kumar PA, Bhanuprakash Reddy G. Ellagic acid inhibits non-enzymatic glycation and prevents proteinuria in diabetic rats. Food Funct. 2016 Mar;7(3):1574-83. doi: 10.1039/c5fo01372k. PubMed PMID: 26902315.
26. Kumar PA, Welsh GI, Raghu G, Menon RK, Saleem MA, Reddy GB. Carboxymethyl lysine induces EMT in podocytes through transcription factor ZEB2: Implications for podocyte depletion and proteinuria in diabetes mellitus. Arch Biochem Biophys. 2016 Jan 15;590:10-19. doi: 10.1016/j.abb.2015.11.003. Epub 2015 Nov 10. PubMed PMID: 26550927.
25. Pasupulati. Advanced glycation end products mediated cellular and molecular events in the pathology of diabetic nephropathy. Biomolecular concepts. 2016; 7(5-6):293.
2015
24. Chitra PS, Swathi T, Sahay R, Reddy GB, Menon RK, Kumar PA. Growth Hormone Induces Transforming Growth Factor-Beta-Induced Protein in Podocytes: Implications for Podocyte Depletion and Proteinuria. J Cell Biochem. 2015 Sep;116(9):1947-56. doi: 10.1002/jcb.25150. PubMed PMID: 25740786.
2014
23. Muthenna P, Raghu G, Kumar PA, Surekha MV, Reddy GB. Effect of cinnamon and its procyanidin-B2 enriched fraction on diabetic nephropathy in rats. Chem Biol Interact. 2014 Oct 5;222:68-76. doi: 10.1016/j.cbi.2014.08.013. Epub 2014 Sep 6. PubMed PMID: 25199697.
22. Kumar PA, Chitra PS, Lu C, Sobhanaditya J, Menon R. Growth hormone (GH) differentially regulates NF-kB activity in preadipocytes and macrophages: implications for GH's role in adipose tissue homeostasis in obesity. J Physiol Biochem. 2014 Jun;70(2):433-40. doi: 10.1007/s13105-014-0321-8. Epub 2014 Feb 15. PubMed PMID: 24532264.
2013
21. Reddy VS, Raghu G, Reddy SS, Pasupulati AK, Suryanarayana P, Reddy GB. Response of small heat shock proteins in diabetic rat retina. Invest Ophthalmol Vis Sci. 2013 Nov 19;54(12):7674-82. doi: 10.1167/iovs.13-12715. PubMed PMID: 24159092.
20. Kumar PA, Chitra PS, Reddy GB. Metabolic syndrome and associated chronic kidney diseases: nutritional interventions. Rev Endocr Metab Disord. 2013 Sep;14(3):273-86. doi: 10.1007/s11154-013-9268-2. Review. PubMed PMID: 24036690.
19. Pasupulati AK, Reddy GB. Nutrition & metabolic syndrome. Rev Endocr Metab Disord. 2013 Sep;14(3):217. doi: 10.1007/s11154-013-9267-3. PubMed PMID: 24052338.
18. Sankeshi V, Kumar PA, Naik RR, Sridhar G, Kumar MP, Gopal VV, Raju TN. Inhibition of aldose reductase by Aegle marmelos and its protective role in diabetic cataract. J Ethnopharmacol. 2013 Aug 26;149(1):215-21. doi: 10.1016/j.jep.2013.06.025. Epub 2013 Jul 1. PubMed PMID: 23827758.
17. Lu C, Kumar PA, Sun J, Aggarwal A, Fan Y, Sperling MA, Lumeng CN, Menon RK. Targeted deletion of growth hormone (GH) receptor in macrophage reveals novel osteopontin-mediated effects of GH on glucose homeostasis and insulin sensitivity in diet-induced obesity. J Biol Chem. 2013 May 31;288(22):15725-35. doi: 10.1074/jbc.M113.460212. Epub 2013 Apr 17. PubMed PMID: 23595986; PubMed Central PMCID: PMC3668731.
16. Pasupulati AK, Menon RK. New insights into growth hormone’s actions on the macrophage: implications for non-growth-related actions of growth hormone. OA Biochemistry. 2013; 1(2):15.
2011
15. Sun J, Kumar PA, Thimmarayappa J, Saini N, Goel P, Maures T, Lu C, Menon RK. Esterase 1 is a novel transcriptional repressor of growth hormone receptor gene expression: a unique noncatalytic role for a carboxyesterase protein. Mol Endocrinol. 2011 Aug;25(8):1351-63. doi: 10.1210/me.2011-0097. Epub 2011 Jun 9. PubMed PMID: 21659478; PubMed Central PMCID: PMC3146247.
14. Kumar PA, Brosius FC 3rd, Menon RK. The glomerular podocyte as a target of growth hormone action: implications for the pathogenesis of diabetic nephropathy. Curr Diabetes Rev. 2011 Jan;7(1):50-5. doi: 10.2174/157339911794273900. Review. PubMed PMID: 21067510; PubMed Central PMCID: PMC4007067.
13. P A, P Y, P S, G B. Effect of the tannoid enriched fraction of Emblica officinalis on α-crystallin chaperone activity under hyperglycemic conditions in lens organ culture. Journal of Biophysics and Structural Biology. 2011; 3(2):30.
2010
12. Kumar PA, Kotlyarevska K, Dejkhmaron P, Reddy GR, Lu C, Bhojani MS, Menon RK. Growth hormone (GH)-dependent expression of a natural antisense transcript induces zinc finger E-box-binding homeobox 2 (ZEB2) in the glomerular podocyte: a novel action of gh with implications for the pathogenesis of diabetic nephropathy. J Biol Chem. 2010 Oct 8;285(41):31148-56. doi: 10.1074/jbc.M110.132332. Epub 2010 Aug 3. PubMed PMID: 20682777; PubMed Central PMCID: PMC2951188.
11. Lu C, Kumar PA, Fan Y, Sperling MA, Menon RK. A novel effect of growth hormone on macrophage modulates macrophage-dependent adipocyte differentiation. Endocrinology. 2010 May;151(5):2189-99. doi: 10.1210/en.2009-1194. Epub 2010 Feb 25. PubMed PMID: 20185763; PubMed Central PMCID: PMC2869256.
2009
10. Kumar PA, Reddy PY, Srinivas PN, Reddy GB. Delay of diabetic cataract in rats by the antiglycating potential of cumin through modulation of alpha-crystallin chaperone activity. J Nutr Biochem. 2009 Jul;20(7):553-62. doi: 10.1016/j.jnutbio.2008.05.015. Epub 2008 Sep 11. PubMed PMID: 18789666.
9. Kumar PA, Reddy GB. Modulation of alpha-crystallin chaperone activity: a target to prevent or delay cataract?. IUBMB Life. 2009 May;61(5):485-95. doi: 10.1002/iub.176. Review. PubMed PMID: 19391162.
2007
8. Anil Kumar P, Bhanuprakash Reddy G. Focus on molecules: aldose reductase. Exp Eye Res. 2007 Dec;85(6):739-40. doi: 10.1016/j.exer.2006.08.002. Epub 2006 Sep 25. Review. PubMed PMID: 16997295.
7. Kumar PA, Kumar MS, Reddy GB. Effect of glycation on alpha-crystallin structure and chaperone-like function. Biochem J. 2007 Dec 1;408(2):251-8. doi: 10.1042/BJ20070989. PubMed PMID: 17696877; PubMed Central PMCID: PMC2267351.
2006
6. Reddy GB, Kumar PA, Kumar MS. Chaperone-like activity and hydrophobicity of alpha-crystallin. IUBMB Life. 2006 Nov;58(11):632-41. doi: 10.1080/15216540601010096. Review. PubMed PMID: 17085382.
2005
5. Kumar PA, Haseeb A, Suryanarayana P, Ehtesham NZ, Reddy GB. Elevated expression of alphaA- and alphaB-crystallins in streptozotocin-induced diabetic rat. Arch Biochem Biophys. 2005 Dec 15;444(2):77-83. doi: 10.1016/j.abb.2005.09.021. Epub 2005 Nov 8. PubMed PMID: 16309625.
4. Kumar PA, Suryanarayana P, Reddy PY, Reddy GB. Modulation of alpha-crystallin chaperone activity in diabetic rat lens by curcumin. Mol Vis. 2005 Jul 26;11:561-8. PubMed PMID: 16088325.
3. Moghaddam MS, Kumar PA, Reddy GB, Ghole VS. Effect of Diabecon on sugar-induced lens opacity in organ culture: mechanism of action. J Ethnopharmacol. 2005 Feb 28;97(2):397-403. doi: 10.1016/j.jep.2004.11.032. Epub 2005 Jan 18. PubMed PMID: 15707781.
2004
2. Kumar MS, Reddy PY, Kumar PA, Surolia I, Reddy GB. Effect of dicarbonyl-induced browning on alpha-crystallin chaperone-like activity: physiological significance and caveats of in vitro aggregation assays. Biochem J. 2004 Apr 15;379(Pt 2):273-82. doi: 10.1042/BJ20031633. PubMed PMID: 14711370; PubMed Central PMCID: PMC1224074.
1. Suryanarayana P, Kumar PA, Saraswat M, Petrash JM, Reddy GB. Inhibition of aldose reductase by tannoid principles of Emblica officinalis: implications for the prevention of sugar cataract. Mol Vis. 2004 Mar 12;10:148-54. PubMed PMID: 15031705.